Obviously, experimentation is king, and heterodyning will not likely work in every situation. I'm sure that the overall design, brace, tiller, nocking point, type of string, individual shooter's style, and split/three under will dictate the best string silencer position. But since I 'discovered' this technique, I have utilized it successfully on three long bows, and a recurve. All with different strings and strand counts, and different braces. It seems to work well for my set ups, and will likely work for some of yours. It does look a little strange at first, but is easy to get used to. I actually prefer the looks now over evenly spaced silencers.
Somewhere, there is a right up on the science behind it. It may have been here, another traditional website, or in traditional bowhunter magazine. It has been some time now since I first read it. It says something along the lines of having one silencer at the 1/4 cancels out the even number frequencies, while the other silencer at the 1/3 cancels out the odd number frequencies. Give it a try, if it doesn't work for you, you can always change it, or you might find that it works great, as I did.