I'd like to see 160s, but 140s would be my lowest, but, it all depends on your target medium as you test BH flight and the penetration you get there. If you shooting into a McKenzie block and getting 4-5" of penetration at 140 then you're good in my book. That would equate for a likely pass-thru on lungs/rib area when you add the lubrication from bodily fluids from the deer. Plus a razor sharp cut-on-contact two blade.
Hog, 150s minimum for me.
Shots need to be on ribs or smaller bones. No shoulder blades. No leg bones/elbows.
Just my humble 2 cents.
Hopefully you'll get others to jump in.