Mike, I have taken 2 Shiras moose in Idaho, a bull and a cow. For the bull I used a 64lb selfbow and a 750 grain ash arrow tipped with a a 4 blade Zwickey Eskimo. Shot was 10 yards, lung hit, complete pass through. Bull went approximately 40 yards. I shot the cow using a 55lb Cari-bow Wolverine. I draw 27". The arrow was an Easton Axis Traditional, 630 grains, 3 blade VPA. Shot was 18-20 yards through the lungs, complete pass through.
Checkout the anatomy post at the beginning of PowWow. There is a great section on moose.
Take close, high percentage shots and you will do great!