WHAT WE WOULD DO MAKES NO DIFFERENCE IN YOUR CIRCUMSTANCES!!!!
I know someone who killed an elephant with a .22
I do not recommend a 22 for elephants.
You should shoot the most weight you can draw, hold, release with accuracy every time you shoot, in any weather conditions, period.
If that means 45 lbs....shoot it...if that means 70 lbs...shoot that. Don't worry about what anyone else does, ever. Do what is right for you.
The deadliest shot is the guy who shoots one bow, year round, same equipment at EVERYTHING, in my opinion. Switching around for rabbits, deer, turkey, hogs, it's going to contribute to poor shooting in my opinion.
Settle on one setup, and use that for all your shooting and you will bring home a lot more to the pot.