Ceme took my words. 45lbs isn't light. Now, 30-35 is light, in my book.
For what it's worth, I have yet to shoot a deer with 40lbs where I didn't get a passthru. That's with Grizzly Stik Sitka's, and 150gr heads, Stingers, Silver Flames and Steelforce Phatheads.
After my shoulder surgery, I killed a deer with a 30lb Kodiak Special, and while I did not get a pass thru on the deer quartered away at 12 yards, I got 14" of penetration in the liver and lungs and a bunch of tasty venison in the freezer.
With 38-40lbs, if you shoot around 450-550grs, use a hair shaving 2 blade or 2 blade with bleeders (like a Stinger or Phathead), keep shots 15 yards and under and don't take low percentage/high risk shots, you'll kill any deer you want. Then again, that criteria applies if you're shooting 60lbs too.
I used to shoot high height compounds, where I felt like Superman and could even sneak an arrow in under low percentage shots and then switched to trad bows in much higher weights than I shoot now and my conclusion is that having to shoot low weights due to shoulder issues has made me a much more patient shot, on animals. Knowing my limitations with low weight, now I only take "gimme" shots, where with higher weights I sometimes thought the power of the bow could make up for the less than perfect shot opportunity.