I consider myself a bowhunter, but before I retired from agriculture, a .22 LR was kept handy for nuisance animals around the barn, like skunks, feral cats, and an occasional raccoon. I made and sold good bit of hay and my primary interest was sellings lambs.
A very accurate .270, (my former deer rifle), was pretty much reserved for woodchucks that were attempting to den, out in my fields, (equipment hazard), and eastern coyotes, who were engaged at every opportunity, in defense of my flock and border collie.