I shot one with a snuffer in the head exposing brains. He ran up the tree and sat beside me 10 feet away at 25 feet up in the air and wiped his face staring at me in anger. It was a bit disconcerting... and I didn't want to shoot that high in the tree and lose my arrow... I thought surely he would die soon, but he eventually ran away to a brush pile... but he certainly wasn't acting right.
The next evening my brother hunts the area and finds a crazed squirrel with half a face sprinting in a 3 foot circle at full speed. He walks right up to him, examines the odd behavior, and arrows him at point blank range, this time through the body with a Muzzy. He places him in an old washtub in the back of the truck when he finishes the evening hunt and drives home 10 miles.
When he arrives, the squirrel is running circles around the tub with the arrow still sticking out... and still half a face and brains exposed.
They get the arrow out and try to squash him to finish him off... but he continues to fight.
At this point its pretty scary so they just turn the demon squirrel loose to the neighborhood.
Probably went on to beat up a few local dogs I suspect.