That's an absolutely huge jump in draw weight; being able to draw the bow and being able to shoot the bow are two different things, trust me. If you really have a draw length that long, you are already far ahead of the game, and don't require as much draw weight to begin with as someone with a short draw (in terms of getting energy for penetration). 45lbs would actually be a pretty big jump, but almost everyone can handle that and it is plenty for deer, especially at your draw. You might be a strong guy, so it's up to you, of course, but I would not recommend jumping up that much at one time. Go in more like five pound increments after 45lbs. Of course, at your draw that's going to be closer to 50lbs, anyway. Good luck.