These are my opinions, take them for what they are worth. Always best to do your own experimenting to find what works best for you.
1. Does each bow have a 'spot' that is best for a silencer, or does that spot move around depending on which silencer you use?
The "sweet spot" should be the same, regardless of what type silencer you use. That spot may change some from bow to bow, even the same bow that is the same length.
2. Seems like there are a lot of different wool silencers out there for instance. Is there a large difference in which type of wool? (asking because the SBD silencer is also a wool puff, just smaller at about half the size. So I wonder if I need the different material, or just a larger puff in general)
I haven't done much with wool. Plan to experiment with some Two Tracks wool silences in the near future (thanks Chuck!). I've always had great results with cat whiskers. In general, more material can help, but it can also hinder.
3. When installing a new string, should it have the same BH as the old one? Or put another way, is the brace height determined by the bow/arrow combo, or the string material/design?
It should be the same or close, but for the best results re-tune. ESPECIALLY if you are changing string materials, strand counts, string makers, or anything else.
I like to start with a "naked" string (no silencers). Try to eliminate one variable at a time.
Get the string shot in. A pre-stretched HMPE ("fast flight") string shouldn't take more than 50-100 shots, if that.
Find the spot in the brace where you have the least noise/shock/vibration. Write it down.
Add silencers. One at the 1/3 point and one at the 1/4 point seems to be the best starting place.
Adjusting the silencers as little as 1" at a time can make a huge difference with some bows.
Other tips to get a bow quieter is a higher brace, heavier arrow, work on your release, and a good nock fit (not too tight). If your arrows aren't the right spine, that can add noise as well as the nock point being too high or too low.