Here's my $5 worth.
Regardless wether 2 or 3 blade. Properly tuned arrows flying straight on impact greatly increases your penetration. If your arrows hits nock right, left, up, down, or nock first
, it won't matter how many blades or how scary sharp they are, they'll have less penetration.
Single bevel grizzly BH's leave a nice mean hole.
I personally use grizzly kodiak 200 gr. on most everything and 125gr snuffer 3 blade with 75gr internal footing on wood shafts for uplands and waterfowl.